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Literature summary for 3.4.21.105 extracted from

  • Kreutzberger, A.J.B.; Ji, M.; Aaron, J.; Mihaljevic, L.; Urban, S.
    Rhomboid distorts lipids to break the viscosity-imposed speed limit of membrane diffusion (2019), Science, 363, eaao0076 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Escherichia coli 16020
-
membrane
-
Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Homo sapiens Q9NX52
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293T cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
GlpP
-
Escherichia coli
RHBDL2
-
Homo sapiens

General Information

General Information Comment Organism
physiological function rhomboid displays a rapid diffusion comparable to the diffusion of small, single-pass transmembrane proteins, with a diffusion coefficient of about 0.8 microm2 per s. The rhomboid fold is able to distort surrounding lipids, overcome the viscosity limit of the membrane, and accelerate its search for substrates Escherichia coli
physiological function rhomboid displays a rapid diffusion comparable to the diffusion of small, single-pass transmembrane proteins, with a diffusion coefficient of about 0.8 microm2 per s. The rhomboid fold is able to distort surrounding lipids, overcome the viscosity limit of the membrane, and accelerate its search for substrates Homo sapiens